Low Density Lipoprotein Cholesterol (LDL)
Low
Density Lipoprotein Cholesterol (LDL) is
a term that indicates the amount of cholesterol carried by the LDL
particle. It is commonly referred to as the “bad” cholesterol
because is can indicate an increased risk of heart disease when the
levels are high. It is actually the LDL particle that does the
damage. The cholesterol is its cargo. As a result of increase
particles and their activity, LDL can build up with other substances
on the walls of the arteries that circulate blood to the heart and
other organs. Over time this build up becomes a thick hardened
deposit that has the potential to block the artery entirely.1
If the blockage occurs in the heart, it causes a heart attack; if
the blockage occurs in the brain, it causes a stroke. In addition to
the slowly occurring risk of arterial blockage, the build up of
cholesterol can suddenly rupture, causing more than 90% of all heart
attacks and strokes.2
According to the
National Heart, Lung, and Blood Institute, the LDL cholesterol level
is a better indicator of risk for a heart attack and stroke than is
total cholesterol. The higher the LDL, the higher the risk for heart
disease or stroke.3
1 What’s the Difference Between LDL and HDL Cholesterol? American Heart Association. 2006. www.americanheart.org
2 Guyton, J.R. Lipid Metabolism and Atherogenesis Overview. Lecture, May 26, 2006.
3 High Blood Cholesterol. National Heart, Lung, and Blood Institute. February, 2006. www.nhlbi.nih.gov

